diff --git a/BioArchLinux/r-ctsv/PKGBUILD b/BioArchLinux/r-ctsv/PKGBUILD
new file mode 100644
index 0000000000..233b10c9a9
--- /dev/null
+++ b/BioArchLinux/r-ctsv/PKGBUILD
@@ -0,0 +1,44 @@
+# Maintainer: Pekka Ristola <pekkarr [at] protonmail [dot] com>
+
+_pkgname=CTSV
+_pkgver=1.4.0
+pkgname=r-${_pkgname,,}
+pkgver=${_pkgver//-/.}
+pkgrel=1
+pkgdesc="Identification of cell-type-specific spatially variable genes accounting for excess zeros"
+arch=(any)
+url="https://bioconductor.org/packages/${_pkgname}"
+license=(GPL3)
+depends=(
+  r-biocparallel
+  r-knitr
+  r-pscl
+  r-qvalue
+  r-spatialexperiment
+  r-summarizedexperiment
+)
+checkdepends=(
+  r-testthat
+)
+optdepends=(
+  r-biocstyle
+  r-testthat
+)
+source=("https://bioconductor.org/packages/release/bioc/src/contrib/${_pkgname}_${_pkgver}.tar.gz")
+md5sums=('4a3f8c7b5398449ea01b312ed7da1f43')
+sha256sums=('c9ab303473fa093de52c3a25dc2e46413399cef5284aa2c177299c03e61fcc02')
+
+build() {
+  mkdir -p build
+  R CMD INSTALL "$_pkgname" -l build
+}
+
+check() {
+  cd "$_pkgname/tests"
+  R_LIBS="$srcdir/build" NOT_CRAN=true Rscript --vanilla testthat.R
+}
+
+package() {
+  install -d "$pkgdir/usr/lib/R/library"
+  cp -a --no-preserve=ownership "build/$_pkgname" "$pkgdir/usr/lib/R/library"
+}
diff --git a/BioArchLinux/r-ctsv/lilac.py b/BioArchLinux/r-ctsv/lilac.py
new file mode 100644
index 0000000000..39dc53390d
--- /dev/null
+++ b/BioArchLinux/r-ctsv/lilac.py
@@ -0,0 +1,17 @@
+#!/usr/bin/env python3
+from lilaclib import *
+
+import os
+import sys
+sys.path.append(os.path.normpath(f'{__file__}/../../../lilac-extensions'))
+from lilac_r_utils import r_pre_build
+
+def pre_build():
+    r_pre_build(
+        _G,
+        expect_needscompilation = True,
+    )
+
+def post_build():
+    git_pkgbuild_commit()
+    update_aur_repo()
diff --git a/BioArchLinux/r-ctsv/lilac.yaml b/BioArchLinux/r-ctsv/lilac.yaml
new file mode 100644
index 0000000000..38b7a05f5a
--- /dev/null
+++ b/BioArchLinux/r-ctsv/lilac.yaml
@@ -0,0 +1,19 @@
+build_prefix: extra-x86_64
+maintainers:
+- github: pekkarr
+  email: pekkarr@protonmail.com
+repo_depends:
+- r-biocparallel
+- r-knitr
+- r-pscl
+- r-qvalue
+- r-spatialexperiment
+- r-summarizedexperiment
+repo_makedepends:
+- r-testthat
+update_on:
+- source: rpkgs
+  pkgname: CTSV
+  repo: bioc
+  md5: true
+- alias: r